Zhi-Hong Wen Selected Research

Excitatory Amino Acids

12/2013	TGF-β1 attenuates spinal neuroinflammation and the excitatory amino acid system in rats with neuropathic pain.
8/2009	N-Methyl-D-aspartate receptor antagonist d-AP5 prevents pertussis toxin-induced alterations in rat spinal cords by inhibiting increase in concentrations of spinal CSF excitatory amino acids and downregulation of glutamate transporters.
5/2006	Hyaluronic acid attenuates osteoarthritis development in the anterior cruciate ligament-transected knee: Association with excitatory amino acid release in the joint dialysate.
3/2006	Protein kinase C inhibitor chelerythrine attenuates the morphine-induced excitatory amino acid release and reduction of the antinociceptive effect of morphine in rats injected intrathecally with pertussis toxin.
5/2005	Increased concentrations of neuro-excitatory amino acids in rat anterior cruciate ligament-transected knee joint dialysates: a microdialysis study.
12/2003	Implications of intrathecal pertussis toxin animal model on the cellular mechanisms of neuropathic pain syndrome.
3/2002	Apraclonidine attenuates the increases in spinal excitatory amino acid release in rats with adjuvant-induced inflammation.

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Zhi-Hong Wen Research Topics

Disease

27	Neoplasms (Cancer) 07/2021 - 05/2007
21	Hyperalgesia 09/2021 - 02/2003
14	Inflammation (Inflammations) 03/2021 - 03/2002
10	Neuralgia (Stump Neuralgia) 09/2021 - 12/2003
8	Pain (Aches) 09/2021 - 09/2014
7	Edema (Dropsy) 11/2017 - 01/2008
6	Parkinson Disease (Parkinson's Disease) 02/2022 - 03/2012
6	Hepatocellular Carcinoma (Hepatoma) 09/2021 - 03/2014
5	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 01/2019
5	Neuroinflammatory Diseases 09/2021 - 10/2009
5	Liver Neoplasms (Liver Cancer) 04/2021 - 01/2011
5	Infections 01/2020 - 01/2016
5	Osteoarthritis 01/2020 - 05/2005
4	Neuroblastoma 02/2022 - 04/2011
4	Carcinogenesis 06/2021 - 01/2016
4	Wounds and Injuries (Trauma) 02/2018 - 01/2013
3	Arthritis (Polyarthritis) 02/2022 - 01/2013
3	Glioblastoma (Glioblastoma Multiforme) 06/2021 - 01/2018
3	Gouty Arthritis 07/2020 - 01/2013
3	Melanoma (Melanoma, Malignant) 01/2020 - 03/2011
3	Asthma (Bronchial Asthma) 05/2019 - 08/2008
3	Spinal Cord Injuries (Spinal Cord Injury) 01/2018 - 09/2015
3	Hypersensitivity (Allergy) 12/2016 - 03/2002
3	Leukemia 10/2016 - 01/2011
3	Atherosclerosis 05/2015 - 12/2010
2	Atopic Dermatitis (Atopic Eczema) 04/2022 - 01/2018
2	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2022 - 01/2018
2	Gout 01/2022 - 01/2013
2	Peripheral Nervous System Diseases (PNS Diseases) 09/2021 - 06/2011
2	Alzheimer Disease (Alzheimer's Disease) 12/2020 - 05/2007
2	Fibrosis (Cirrhosis) 12/2020 - 05/2019
2	Allergic Rhinitis 07/2020 - 07/2018
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 09/2018
2	Osteosarcoma (Osteogenic Sarcoma) 01/2020 - 01/2018
2	Sepsis (Septicemia) 10/2019 - 01/2017
2	Lung Neoplasms (Lung Cancer) 01/2019 - 08/2013
2	Prostatic Neoplasms (Prostate Cancer) 06/2018 - 12/2016
2	Body Weight (Weight, Body) 06/2018 - 04/2018
2	Breast Neoplasms (Breast Cancer) 01/2018 - 10/2012
2	Experimental Liver Neoplasms 01/2018 - 03/2014
2	Rheumatoid Arthritis 01/2017 - 01/2013

Drug/Important Bio-Agent (IBA)

19	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2009
12	Pharmaceutical PreparationsIBA 07/2021 - 06/2012
8	Therapeutic UsesIBA 03/2021 - 01/2013
7	CarrageenanIBA 11/2017 - 01/2008
7	Excitatory Amino AcidsIBA 12/2013 - 03/2002
6	LipopolysaccharidesIBA 10/2019 - 01/2012
6	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 02/2018 - 07/2004
5	AntioxidantsIBA 02/2022 - 01/2012
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2019
4	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2021 - 08/2013
4	CytokinesIBA 09/2021 - 01/2012
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2019 - 03/2002
4	dihydroaustrasulfone alcoholIBA 01/2018 - 12/2010
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2016 - 12/2013
4	Melanins (Melanin)IBA 01/2016 - 01/2012
4	lemnalolIBA 02/2015 - 01/2008
4	Pertussis ToxinIBA 08/2009 - 02/2003
4	Dialysis SolutionsIBA 08/2009 - 12/2003
3	Biological ProductsIBA 01/2022 - 01/2012
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2021 - 01/2019
3	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 07/2021 - 09/2016
3	hepatoma-derived growth factorIBA 12/2020 - 10/2012
3	Uric Acid (Urate)IBA 07/2020 - 01/2013
3	Antimicrobial PeptidesIBA 01/2020 - 06/2015
3	Matrix Metalloproteinases (MMPs)IBA 05/2019 - 08/2013
3	heteroneminIBA 01/2019 - 12/2016
3	11-dehydrosinulariolideIBA 10/2016 - 03/2012
3	Monophenol Monooxygenase (Tyrosinase)IBA 01/2015 - 03/2011
3	Analgesics (Analgesic Drugs)IBA 06/2014 - 03/2002
3	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 06/2014 - 12/2009
3	Superoxides (Superoxide)IBA 08/2012 - 01/2011
3	Morphine (MS Contin)FDA LinkGeneric 08/2009 - 12/2003
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 08/2009 - 02/2003
3	N-Methylaspartate (NMDA)IBA 08/2009 - 02/2003
3	Glutamic Acid (Glutamate)FDA Link 08/2009 - 12/2003
2	Oxidopamine (6 Hydroxydopamine)IBA 02/2022 - 03/2012
2	EnzymesIBA 01/2022 - 01/2019
2	sinularinIBA 04/2021 - 09/2012
2	Collagen Type II (Type II Collagen)IBA 03/2021 - 01/2017
2	Nasal SpraysIBA 07/2020 - 07/2018
2	Budesonide (Pulmicort)FDA LinkGeneric 07/2020 - 07/2018
2	EtoricoxibIBA 07/2020 - 01/2020
2	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2020 - 03/2014
2	Adrenal Cortex Hormones (Corticosteroids)IBA 05/2019 - 08/2008
2	MicroRNAs (MicroRNA)IBA 01/2019 - 01/2016
2	Interleukin-4 (Interleukin 4)IBA 11/2018 - 02/2016
2	Celecoxib (Celebrex)FDA Link 01/2018 - 03/2014
2	p38 Mitogen-Activated Protein KinasesIBA 07/2017 - 08/2005
2	excavatolide BIBA 01/2017 - 04/2015
2	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 12/2016 - 04/2011
2	CollagenIBA 11/2016 - 01/2013

Therapy/Procedure

9	Therapeutics 04/2021 - 03/2011
3	Drug Therapy (Chemotherapy) 06/2021 - 01/2013
3	Intra-Articular Injections 07/2020 - 05/2008
3	Spinal Injections 09/2016 - 02/2003
2	Oral Administration 03/2021 - 11/2012
2	Moxibustion 07/2020 - 07/2018
2	Immunotherapy 11/2018 - 01/2018
2	Injections 04/2018 - 12/2016